Radiotherapy

Skeletonization for isocentre selection in Gamma Knife® Perfexion™
Gamma Knife® Perfexion™ (PFX) is used for delivering radiosurgery plans to treat lesions and tumours in the brain by means of …
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A fluence map optimization model for restoring traditional fractionation in IMRT treatment planning
One of the core problems in intensity modulated radiation therapy (IMRT) treatment planning is the fluence map optimization (FMO) …
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Optimization methods for patient positioning in Leksell Gamma Knife Perfexion
We study inverse treatment planning approaches for stereotactic radiosurgery using Leksell Gamma Knife Perfexion (PFX, Elekta, …
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Automated inverse planning over a continuous path using Gamma Knife Perfexion
Leksell Gamma Knife Perfexion (PFX, Elekta, Stockholm, Sweden) is the latest generation of stereotactic radiosurgery delivery units, …
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Automated treatment planning for a dedicated multi-source intra-cranial radiosurgery treatment unit accounting for overlapping structures and dose homogeneity
Purpose: The purpose of this work is to advance the two-step approach for Gamma Knife® Perfexion™ (PFX) optimization to account for …
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Computational enhancements to fluence map optimization for total marrow irradiation using IMRT
The fluence map optimization (FMO) problem is a core problem in intensity modulated radiation therapy (IMRT) treatment planning. …
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Incorporation of delivery times in Leksell Gamma Knife R Perfexion TM treatment optimization
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Optimization methods for large-scale radiotherapy problems
Optimization techniques are commonly applied to treatment design problems arising in radiation therapy. Previous literature on the …
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Optimization of dose schedules in radiotherapy
Purpose: Fractionation in radiotherapy is the scheduled break up of a total treatment dose into individual doses. The goal of this …
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A tractable mixed-integer model to design stereotactic radiosurgery treatments
We present a new approach to automatically generate complete stereotactic radiosurgery treatment plans for Gamma Knife⃝R PerfexionTM …
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